IHSS&IWA26 / BRNO / CZECHIA / 23–28 August 2026 BOOK OF ABSTRACTS 96 NOM and Aquatic Systems Thursday, 27 August 2026 / Hall C how DOM source and disinfectant type influence DBP formation. Additionally, targeted DBP analysis was performed on simulated disinfection experiments using GC–MS/MS to establish associations between DBP formation and HRMS-derived molecular features. The combination of nontargeted and targeted approaches enables the identification of molecular features linked to DBP formation and provides a more comprehensive understanding of precursor–product relationships across different water matrices and disinfectants. Overall, our results advance the molecular-level understanding of DOM transformations during disinfection and highlights the combined influence of disinfectant type and DOM origin on X-DOM formation. These findings support improved identification of DBP precursors and contribute to the development of more informed strategies for DBP control in drinking water treatment. Acknowledgement This research was funded by the European Union, Project 101081728-intoDBP. Francisco Zafra acknowledges the Spanish State Research Agency of the Spanish Ministry of Science and Innovation and European Social Fund+ for his Predoctoral fellowship PRE2021-099897 funded by MCIN/ AEI/ 10.13039/501100011033 and FSE+ .We also acknowledge the funding received by Economy and Knowledge Department of the Catalan Government through Consolidated Research Groups (ICRA-ENV 2021 SGR 01282 and ICRA-Tech 2021 SGR 01283), as well as from the CERCA program.
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